NIPER, GUWAHATI conducts research in different areas of pharmaceutical sciences keeping in view the national and local needs.
Development of synthetic riboswitches to suppress gene expression in case of various life-threatening diseases.
Development of deoxyribozymes, which can degrade RNA of various oncogenes. Generation of various novel protein coding sequences, which can be further developed as biopharmaceuticals.
Suitability of G-quadruplexes as gene regulation tool in cancer and other diseases.
Directed evolution of therapeutic proteins for enhanced activity and least immunogenicity.
Study in the field of Molecular Hematology to observe the molecular details in various diseases like Multiple Myeloma, Acute Myeloid Leukemia, Chronic Myeloid Leukemia, Myodisplastic syndrome.
Molecular genomics and expression of various targets in Ischemia Stroke disorder etc.
Pharmacogenomics study in Diabetes, use of drugs like clopidogrel and its pharmacogenomic approaches.
Investigation in Molecular pathophysiology of various targets in Neuropathic pain and its future treatment.
Study in the field of Proteomics to develop various target drugs for therapeutic approaches.
Protective effect of Carissa carandas against cyclophosphamide-induced toxicity.
Evaluate the effect of Naringenin and Crocetin on cyclophosphamide-induced testicular toxicity.
Studies on anti-tumor activity of various plants available in the North East region Effect of Ocimum sanctum in experimental diabetic neuropathy.
Anti-inflammatory activity of Morabulus jalepa in acute and chronic models of inflammation in rats.
Effect of Green tea polyphenols on the pharmacokinetics of Paclitaxel
Evaluate anti-inflammatory activity of Hibiscus rosa sinensis in rats.
Protective effect of mangiferin against lipopolysaccharide-induced depressive and anxiety-like behaviour in mice.
Studies on Neurodegenerative diseases like Parkinson’s, Alzheimer’s etc.
Pharmacological studies of various anti cancer agents and plant extracts.
Pharmacological studies in depression.
Adverse Drug Reaction (ADR) monitoring
Drug Drug Interaction (DDI) studies
ADR monitoring of Anti-TB therapy
Currently three projects are going on at NIPER-Guwahati